Multiple Behavior Phenotypes of the Fragile-X Syndrome Mouse Model Respond to Chronic Inhibition of Phosphodiesterase-4D (PDE4D).

Sci Rep · 2017 · PMC5677090 · PMID 29116166

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1000

boldest claim

The sentences

highly significantp < 0.001actually significant

Based on two-way ANOVA, there was a highly significant interaction between treatment and genotype ( F (1,36) = 41.78, p < 0.001 ).

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showed a trendp < 0.1so close (0.05 < p ≤ 0.1)

The spine data also showed a trend by animal ( N = 10 mice per group; p < 0.1 ) for an increase in mature spines on layer 3 pyramidal cells after treatment with BPN14770, while there was no change in spine morphometry on layer 5 pyramidal neurons (Sup Fig. 2 ).

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