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Why European and United States drug regulators are not speaking with one voice on anti-influenza drugs: regulatory review methodologies and the importance of 'deep' product reviews.

Health Res Policy Syst · 2017 · PMC5680823 · PMID 29121959

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However, she also noted that significant efficacy was not demonstrated in the small subgroup of elderly patients, where a pooled analysis failed to reach statistical significance [ 33 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.