Local High-Dose Radiotherapy Induces Systemic Immunomodulating Effects of Potential Therapeutic Relevance in Oligometastatic Breast Cancer.

Front Immunol · 2017 · PMC5681493 · PMID 29163540

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nearly significantno p-value reported

Although confirmation in larger series is warranted, our results also showed a parallel, nearly significant correlation between in vitro ADCC efficiency and p65 nuclear translocation, thus suggesting that the improvement in systemic NK cell activation may favor NK cell-dependent mechanisms, particularly trastuzumab-mediated ADCC in the HER2 + subset ( 22 ).

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