However, the inflammation-induced expression of p65 showed a trend of decreasing in the ovariectomized groups receiving increasing doses of P4 (Fig. 2B ).
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Progesterone attenuates temporomandibular joint inflammation through inhibition of NF-κB pathway in ovariectomized rats.
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More importantly, the scores in ovariectomized groups showed a decreasing trend with the increasing doses of P4 (Fig. 1E ).