STING expression and response to treatment with STING ligands in premalignant and malignant disease.

PLoS One · 2017 · PMC5685615 · PMID 29135982

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did not reach statistical significanceno p-value reported

Treatment with STING ligands resulted in a significant secretion of IFNβ, and a trend towards increased TNFα secretion, but this did not reach statistical significance ( Fig 2D ) suggesting that as with other innate stimuli used to treat papilloma, production of type I IFN may be a major mechanism of action.

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