At the cutoff level of 376 nmol/L, the 2.4% bias is ~9 nmol/L, which is probably not significant given the analytical CV of most cortisol immunoassays of 4% to 8%.
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Salivary Cortisol and Cortisone After Low-Dose Corticotropin Stimulation in the Diagnosis of Adrenal Insufficiency.
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