Barely Significant
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5-Fluorouracil and irinotecan (SN-38) have limited impact on colon microbial functionality and composition <i>in vitro</i>.

PeerJ · 2017 · PMC5694655 · PMID 29158969

1
hedged sentence
0.0650
closest p · 1.3× alpha
0.0650
boldest claim

The sentences

showed a trendp = 0.065so close (0.05 < p ≤ 0.1)
At the genus level, the 5-FU treatment showed a trend in increased relative abundance of Bacteroides from 24.4 ± 13.2% to 41.1 ± 11.6% ( p = 0.065) and decreased abundance of Escherichia / Shigella from 19.7 ± 17.1% to 8.9 ± 7.2% ( p = 0.23) in the lumen for 5 out of 6 donors.

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