Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the North-West of England.

Although this did not reach statistical significance in comparison to individuals recruited in autumn/winter (60.2±22.7 and 45.6±25.9 nmol/L, respectively), ( figure 1B ), these data are in agreement with previous clinical studies demonstrating that vitamin D status varies seasonally, with concentrations of 25(OH)D increasing in spring and peaking at summer. 33 The higher total serum 25(OH)D concentrations in patients with CFS/ME during the autumn/winter months is likely to be a result of increased vitamin D intake.

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