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Switching From Immediate-Release to Delayed-Release Prednisone in Moderate to Severe Rheumatoid Arthritis: A Practice-Based Clinical Study.

Rheumatol Ther · 2017 · PMC5696287 · PMID 28819927

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a clear trendno p-value reported
One showed a clear trend for improved short-term outcomes using DR-prednisone as compared to IR-prednisone [ 11 ], and another showed that 7 mg of DR-prednisone given in the evening achieved a similar percentage reduction in mean duration of morning stiffness as achieved with twice the dose of prednisolone in the morning [ 12 ].

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