Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients.

Ozone was associated with a 6.6% increase in tPA with a 3 day lag (95% CI = 0.4, 13.2; p = 0.04), and a near-significant 6.3% increase with a 4 day lag (95% CI = −0.1, 13.1; p = 0.05; Fig. 4 ), per IQR of ozone.

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There was a significant 19.5% decrease for the 5 day moving average (95% confidence intervals (CI) = −34.0, −1.7; p = 0.03), and a borderline significant 11.7% decrease with a lag of 4 days (95% CI = −22.1, 0.0; p = 0.05).

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There was also a 3.3% marginally significant decrease in diastolic blood pressure with a 2 day lag (95% CI = −6.6, 0.2; p = 0.07).

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