Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.

Hepatology · 2017 · PMC5698707 · PMID 28498614

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Also, plasma TCA levels showed a trend to decrease in OATP1B1‐humanized Slco1a/1b knockouts after myrcludex B administration.

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