Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.

Nat Commun · 2017 · PMC5701046 · PMID 29170503

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showed a trendno p-value reported

Intriguingly, both T-cell exhaustion markers and IFN-signaling genes showed a trend towards up-regulation in tumors from patients with clinical benefit, with the majority of the genes not reaching significance.

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