Echinacoside's nigrostriatal dopaminergic protection against 6-OHDA-Induced endoplasmic reticulum stress through reducing the accumulation of Seipin.

J Cell Mol Med · 2017 · PMC5706584 · PMID 28767194

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As shown in Figure 3 D, 3 weeks post‐lesion, unilateral lesioned rats injected with 6‐OHDA showed a trend of increased contralateral rotation after apomorphine administration compared with the vehicle group ( P < 0.01), but there was no significant difference between the 6‐OHDA group and the 6‐OHDA plus ECH group ( P > 0.05).

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