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Colonization, mortality, and host cytokines response to enterohemorrhagic <i>Escherichia coli</i> in rabbits.

Oncotarget · 2017 · PMC5706807 · PMID 29212161

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showed a trendno p-value reported
The outbreak of EHEC in developed countries such as the United States, Japan, Canada and the United Kingdom showed a trend of increasing year by year.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.