Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4.

Am J Drug Alcohol Abuse · 2017 · PMC5706968 · PMID 28448718

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nominally significantno p-value reported

Exclusive cannabis use compared to combined cannabis and tobacco showed no significant difference in DNA methylation ( p = 0.48). Discussion Here we report a nominally significant association between cannabis use during pregnancy and increased DRD4 promoter methylation at one CpG site (CpG11:636796, hg38) in infants, which remained after adjustment for concurrent tobacco use.

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