Barely Significant
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Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM.

PLoS One · 2017 · PMC5708629 · PMID 29190817

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a significant trendno p-value reported
There was a significant trend of increasing percentage of men testing positive for p16/Ki67 immunostaining with increasing histologic severity of disease, from 23% of men without dysplasia to 41% for men with HSIL (P trend = 0.004).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.