Distinctive pathological and clinical features of lung carcinoids with high proliferation index.

Although also the Ki-67 thresholds here analysed did not reach statistical significance in multivariate analysis, it is interesting to note that the 10% cut-off was able to tease out a category of tumours harbouring dismal prognosis even within the restricted category of ACs, whereas Rindi’s grade did not hold significant prognostic information in this subset of patients.

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