miRNome Profiling in Bicuspid Aortic Valve-Associated Aortopathy by Next-Generation Sequencing.

Int J Mol Sci · 2017 · PMC5713463 · PMID 29165337

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showed a trendno p-value reported

Twenty-one miRNAs showed a trend for different expression between less and severely dilated segments.

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highly significantno p-value reported

Validation of Selected microRNAs Using qRT-PCR Among the 12 differentially expressed miRNA between the BAV and the TAV group, five highly significant dysregulated (miR-424-3p, miR-486-3p, miR-550a-3p, miR-3158-3p, miR-3688-3p) whose target genes were significantly enriched in functional pathways related to BAV aortopathy were selected for further validation.

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