Barely Significant
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Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase.

Nucleic Acids Res · 2017 · PMC5714138 · PMID 29036494

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a clear trendno p-value reported
The grouping of histogram data by the correct RNA nucleotide in the active site shows a clear trend that the substitution of G is strongly discriminated against in all types of selection, and that most errors appear as substitutions of C.

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