Barely Significant
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Dependence of ventilation image derived from 4D CT on deformable image registration and ventilation algorithms.

J Appl Clin Med Phys · 2013 · PMC5714535 · PMID 23835389

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quite significantno p-value reported
However, if there is a misregistration between lung and much denser tissue, such as chest wall or large artery, then the change in HU is quite significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.