IL-4 driven transcription factor FoxQ1 is expressed by monocytes in atopic dermatitis and stimulates monocyte migration.

5A ). Since MCP-1 had pronounced effect on migration of FoxQ1 expressing RAW cells, we tested whether FoxQ1 stimulates expression of MCP-1 receptor CCR2, and found that there was a tendency for increased expression of CCR2 in RAW-FoxQ1 clones that did not reach statistical significance (Fig. 5B , p = 0.063, Mann-Whitney U test).

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