Structural insights into the potency of SK channel positive modulators.

Sci Rep · 2017 · PMC5719431 · PMID 29214998

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a strong trendno p-value reported

A strong trend exists between the interaction energy of the compounds within their binding site calculated from the crystal structures, and the potency of these compounds in potentiating the SK2 channel current determined by electrophysiological recordings.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.