Double-Dose Versus Standard-Dose Clopidogrel According to Smoking Status Among Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention.

Overall, nonsmokers, in comparison to current smokers, showed a trend for a higher rate of major bleedings (166 [1.5%] versus 71 [1.1%]; HR 1.32, 95% CI, 0.97–1.79, P =0.077), as displayed in Table 2 .

also in 53,322 other papers

In comparison to non‐, light‐, and moderate smokers, heavy smokers (consuming ≥20 cigarettes/d) showed a highly significant reduction of the primary end point, the rates of MI and stent thrombosis ( P for all <0.0001), without relevant increase in bleeding risk, if treated with a double‐ compared with a standard‐dose clopidogrel regimen (Table 3 ).

also in 132,142 other papers