Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor.

Neurotherapeutics · 2017 · PMC5722756 · PMID 28593439

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did not reach statistical significanceno p-value reported

The analysis showed a statistically significant difference in the concentration of interferon (IFN)-γ (null: 1765.9 ± 1146.1 pg/ml; sIL23R: 5691.3 ± 2639.3 pg/ml; p = 0.016), as well as a trend toward higher production of granulocyte macrophage colony-stimulating factor (null: 146.2 ± 106.6 pg/ml; sIL23R: 337.4 ± 188.0 pg/ml; p = 0.083), which did not reach statistical significance.

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