Diminution of Heart Rate Variability in Bipolar Depression.

Maudsley scores also tended to be negatively correlated with baseline LF-HRV ( r = −0.255, p = 0.127) and baseline HP ( r = −0.274, p = 0.101), although the relationship did not reach statistical significance (Table 2 ).

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Visual inspection of these two figures indicates a flat time course of RSA and LF-HRV in the escitalopram + celecoxib group whereas the time course of change in the escitalopram + placebo group indicates a possible trend toward reduction in both components.

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