In addition, TGF-β/FBS-treated COPD ASMCs had significantly lower mitochondrial ROS levels, and healthy smoker ASMCs showed a trend towards reduced levels, compared to healthy nonsmoker ASMCs ( figure 6b ).
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In contrast, the GSH/GSSG ratio in TGF-β/FBS-treated COPD ASMCs was higher compared to healthy nonsmoker ASMCs, while healthy smoker ASMCs showed an increasing trend ( figure 6a ).