A comparison of intravenous iron versus oral iron/no iron (five trials) showed a greater reduction in ESA dose, although this did not reach statistical significance (weighted mean difference, 95% CI: −2,433 [−5183, 318] units/week).
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Intravenous iron and erythropoiesis-stimulating agents in haemodialysis: A systematic review and meta-analysis.
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The sentences
There were fewer patients who reported adverse effects with IV iron, but the result did not achieve significance: (12 studies, 1488 patients; risk difference −0.09, 95% CI 0.19 to 0.00; I 2 = 85%).