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Decreased EDHF-mediated relaxation is a major mechanism in endothelial dysfunction in resistance arteries in aged mice on prolonged high-fat sucrose diet.

Physiol Rep · 2017 · PMC5727270 · PMID 29212858

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As shown in Figure 4 B, myogenic tone was decreased in MA 2 from aged HFS compared with young HFS, but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.