Novel active agents in patients with advanced NSCLC without driver mutations who have progressed after first-line chemotherapy.

29 In the squamous population, a numerically longer median OS in the ramucirumab arm did not reach statistical significance (n=328; 9.5 months vs 8.2 months; HR 0.88, 0.69 to 1.13; p=0.32). 28 In a univariate exploratory analysis, patients with time since start of prior therapy of <9 months had a longer OS in the ramucirumab arm versus the placebo arm (HR 0.75, 95% CI 0.64 to 0.88). 28 In REVEL, the most frequently obse

also in 111,027 other papers