Overall treatment effect in OS did not reach statistical significance, neither in the individual trials, nor when the data were pooled (HR 0.91 (95% CI 0.78–1.05))( Figure 4 ).
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Clinicopathological factors influencing outcome in metastatic colorectal cancer patients treated with fluoropyrimidine and bevacizumab maintenance treatment vs observation: an individual patient data meta-analysis of two phase 3 trials.
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