Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model.

Neuropsychopharmacology · 2018 · PMC5729551 · PMID 28540928

Europe PMC DOI

hedged sentences

0.0830

closest p · 1.7× alpha

0.0830

boldest claim

The sentences

tendency towards significancep =0.083so close (0.05 < p ≤ 0.1)

An interaction between IL-18 and severe anxiety with methylation of this CpG cite showed a tendency towards significance in the total population ( p =0.083) and a significant interaction among women ( p =0.014).

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borderline significantno p-value reported

In two other sites in the same region (cg08341874 and cg21593923), borderline significant associations with anxiety was also observed ( p -values 0.041 and 0.048).

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