Dnmt3a is an epigenetic mediator of adipose insulin resistance.

Additionally, gene expression analysis showed a nonsignificant trend toward reduced expression of proinflammatory genes such as Tnfa and Ccl2 (which encodes MCP-1) in the eWAT of Dnmt3a AdiKO mice ( Figure 4—figure supplement 5A ).

also in 5,406 other papers

In our studies, albeit it did not reach statistical significance, there was a trend toward increased mRNA expression of Adipoq in both L1 and primary Dnmt3a KO adipocytes (not shown).

also in 111,027 other papers