The majority of T-cells exhibited simultaneous production of both IFN-γ and TNF-α, and this proportion increased from 54.7% in younger donors to 73.5% in older people although this did not reach statistical significance (Figure 4 ).
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Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8<sup>+</sup> T-Cell Repertoire in Older People.
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