Cellular pharmacodynamic effects of Pycnogenol® in patients with severe osteoarthritis: a randomized controlled pilot study.

BMC Complement Altern Med · 2017 · PMC5732384 · PMID 29246219

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did not reach statistical significanceno p-value reported

The release of sulfated glycosaminoglycans (sGAG) into synovial fluid was lower in the group treated with Pycnogenol® compared to untreated controls although this effect did not reach statistical significance (Table 5 ).

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