Analysis of polypharmacy effects in older patients using Japanese Adverse Drug Event Report database.

PLoS One · 2017 · PMC5739473 · PMID 29267348

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For renal disorder, advanced polypharmacy showed a trend of higher adjusted RORs because the adjusted ROR [1.82 (1.76–1.88)] of administered drugs (≥ 10) group was higher than that [1.27 (1.24–1.31)] of the number of administered drugs (5–9) group ( Table 2 ).

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