Transferrin receptor 1 upregulation in primary tumor and downregulation in benign kidney is associated with progression and mortality in renal cell carcinoma patients.

Oncotarget · 2017 · PMC5739796 · PMID 29291011

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

a strong trendp=0.055so close (0.05 < p ≤ 0.1)

In multivariable analyses adjusting for tumor pathology (and age for overall survival analyses), ccRCC primary tumor TfR1 level remained significantly associated with metastasis-free and overall survival outcomes (p<0.05 each); with a strong trend towards a significant independent association with cancer-specific survival (p=0.055).

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