High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia.

In the favourable risk group, we observed a close correlation of % LSC (from total CD45/SSC blasts cells) with OS and quite significant for DFS, with longer survival for patients with lower level of CD34+CD38- LSC < 1% (median of OS and DFS not attempt > 50%) compared with patients where %LSC was > 1% (median of OS 21.5 mo and for DFS 10.4 mo respectively), P- value = 0.0005 and 0.06.

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