miRNA profiling identifies deregulated miRNAs associated with osteosarcoma development and time to metastasis in two large cohorts.

Mol Oncol · 2018 · PMC5748490 · PMID 29120535

Europe PMC DOI

hedged sentences

0.0065

closest p · 0.1× alpha

0.0880

boldest claim

The sentences

highly significantP = 0.0065actually significant

The association between expression level and poor prognosis in terms of earlier development of distant metastases was highly significant in the validation cohort ( P = 0.0065 and 0.0074, respectively) (Fig.

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borderline significantP = 0.0880so close (0.05 < p ≤ 0.1)

For the overall survival analysis, two miRNAs (miR‐128‐3p and miR‐34a‐3p) were borderline significant in the discovery cohort ( P = 0.0880 and 0.0760, respectively).

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a strong trendno p-value reported

Also, miR‐664a‐3p showed a strong trend toward differential expression (Table S9 and Fig.

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