The group of VD combination boost showed a trend to induce higher levels of IFN-γ+ splenic CD8 T cell responses than those in the VLP boost group (D-V-M) although there is no statistical difference between the two groups after second boost with rMVA.
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Vaccination with Combination DNA and Virus-Like Particles Enhances Humoral and Cellular Immune Responses upon Boost with Recombinant Modified Vaccinia Virus Ankara Expressing Human Immunodeficiency Virus Envelope Proteins.
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