Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.

Furthermore, a weighted polygenic risk score (PRS) made from the 18 SNPs common between the two datasets showed a nominally significant association ( P < 0.05) with the oral glucose tolerance test derived variables area under the curve (AUC) for insulin, AUC for insulin/AUC for glucose, insulin at 30 minutes and insulin sensitivity index ( S6 Table ).

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