Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci.

Of these, 22,296 were nominally significant ( p < 0.05) and 4192 were significant to a genome-wide Bonferroni level ( p < 1 × 10 −7 , linear mixed model) for GWAS risk haplotype-capturing SNP allelic count.

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These younger repeats still possess mobilisation ability 39 and are more likely to be significant contributors to the population variation and haplotypic differences through direct and regional positional effects.

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