Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation.

Int J Mol Sci · 2017 · PMC5751363 · PMID 29257109

Europe PMC DOI

hedged sentences

0.1670

closest p · 3.3× alpha

0.1670

boldest claim

The sentences

did not reach statistical significancep = 0.167not close (p > 0.1)

Calcifediol and doxercalciferol also showed the tendency to decrease IL-1β level, however, the observed decrease did not reach statistical significance (calcifediol: 84.7 ± 8.4%, p = 0.167; doxercalciferol: 73.1 ± 9.4%, p = 0.054).

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highly significantno p-value reported

However, all of the observed mechanisms result in a reduction of total Aβ level, which is highly significant and much more pronounced.

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