Quantitative differences consisted of PPI betweenness, as well as pathway closeness and betweenness being highly significantly negatively correlated with F* while they were only weakly significant or nonsignificant with the ESC data set.
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The Evolution of Gene-Specific Transcriptional Noise Is Driven by Selection at the Pathway Level.
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We further note that while highly significant, the size of this effect is small, with a mean difference in relative expression of −1.10% ( Figure S1 ).