Nano-Encapsulation of Bilirubin in Pluronic F127-Chitosan Improves Uptake in β Cells and Increases Islet Viability and Function after Hypoxic Stress.

Cell Transplant · 2017 · PMC5753985 · PMID 29251115

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This study showed a trend toward a protective effect of 5μM nBR in insulinoma cell line (INS-R3) cells exposed to hypoxic stress ( Fig. 6 ), but protective effects were less apparent than those seen in intact murine islets ( Figs. 8 and 9 ).

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