It is clear that this transcriptional reprogramming is incomplete, since at each subsequent transition during differentiation, a large number of different genes become differentially expressed, with a marked trend towards overexpression of transcripts in emerin-null cells, consistent with a less repressive nuclear environment.
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Expression Profiling of Differentiating Emerin-Null Myogenic Progenitor Identifies Molecular Pathways Implicated in Their Impaired Differentiation.
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