The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature.

Patients produced reduced output relative to controls, demonstrated in their performance on fluency tasks and spoken picture description (CJT: 53.3%) On the picture description test, patients produced fewer words altogether (p = .006) and proportionately fewer nouns (p = .005), while the difference also approached significance with respect to verbs (p = .028).

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