The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumor-reactive T cells.

It appeared that antibiotics exposure reduced T cell activation induced by CTX, as reflected by decreased cell proliferation measured by Ki-67 stain in both CD4+ and CD8+ T cells, although the change in CD8+ T cells did not reach statistical significance (Figure 2A ).

also in 111,027 other papers