Dose escalation by image-guided intensity-modulated radiotherapy leads to an increase in pain relief for spinal metastases: a comparison study with a regimen of 30 Gy in 10 fractions.

In conclusion, in comparison with the 30-Gy regimen, the dose-escalation regimen with conventionally-fractionated IG-IMRT showed a trend of achieving better dosimetric parameters, increasing pain relief and potentially improving the quality of life for patients with spinal metastases, and thus being recommended for these patients, especially those with a long life expectancy.

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