3 In addition to the upregulation of BIM and PUMA proteins after apoptosis induction in EBV-loss cells, increased expression of BIM and PUMA transcripts was also observed compared with EBV-positive cells, although this did not reach statistical significance.
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Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
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