Effects of physical activity on colorectal cancer risk among family history and body mass index subgroups: a systematic review and meta-analysis.

When comparing across BMI subgroups, there were generally no significant differences between low and high BMI relative risks, with the exception of case-control studies ( p = 0.053) and studies of rectal cancer ( p = 0.052), which bordered on significance, in addition to the study by Hou et al.

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While the differences in these variables are only statistically significant in the high BMI group, there was a clear trend across both BMI subgroups showing that measurement of adulthood or lifetime physical activity was associated with the most beneficial effect on the risk of CRC.

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